Process for preparing 1,2,4-triazole nucleosides

Details Process for preparing 1,2,4-triazole nucleosides Process for preparing 1,2,4-triazole nucleosides

1977-12-22

1979-02-06

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 24, 536 26, 536 27, 536 28, 536 29, C07H 1700, C07H 1906

Patent

active

041385470

ABSTRACT:
1-.beta.-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide is prepared by a process wherein a suitably substituted formimidic acid hydrazide is condensed with a blocked derivative of D-ribose and the intermediate is ring closed with a reagent which donates one carbon atom to yield a 3-substituted-1-(blocked .beta.-D-ribofuranosyl)-1,2,4-triazole. Treatment of this intermediate with ammonia and/or removal of the blocking group yields the product.

REFERENCES:
patent: 3798209 (1974-03-01), Witkowski
patent: 4021542 (1977-05-01), Schmidt

Affiliated with

Also associated with

Rating

Process for preparing 1,2,4-triazole nucleosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing 1,2,4-triazole nucleosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing 1,2,4-triazole nucleosides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-892398