Process for preparing 1,1'- (1,4- phenylenebis (methlene)-Bis 1,

Details Process for preparing 1,1'- (1,4- phenylenebis (methlene)-Bis 1, Process for preparing 1,1'- (1,4- phenylenebis (methlene)-Bis 1,

1997-11-12

1998-09-01

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564 90, 564153, 564160, C07C30300, C07C23300

Patent

active

058012818

ABSTRACT:
An improved process for preparing comprising the selective functionalization of an acyclic tetraamine, and subsequent dimerization and hydrolyzation/tosylation to obtain a 1,4-phenylenebis-methylene bridged hexatosyl acyclic precursor in a first step, the cyclization of said precursor to obtain a hexatosyl cyclam dimer in a second step, and the detosylation of said cyclam dimer in a third step followed by basification to obtain the desired

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