Process for preparation of thiophenes

Details Process for preparation of thiophenes Process for preparation of thiophenes

1979-05-07

1981-08-04

Randolph, John D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

2602391, 2603433R, 2603435, 260456P, 260456R, 2604654, 544 28, 549 74, 549 78, 549 79, 560146, 560184, 560192, 560219, 562568, 562571, 562586, 562598, C07C 69602

Patent

active

042823730

ABSTRACT:
Compounds of the formula (II): ##STR1## wherein X is halogen, hydroxyl or functionalized hydroxyl; Y is halogen, hydroxyl or alkoxy; R.sup.1 is a carboxylic acid group and ester thereof and amide derivative thereof or cyano; and R.sup.2 is hydrogen, a hydrocarbon, a heterocycle, a carboxylic acid group, a carboxylic acid ester, a carboxylic acid amide derivative, acyl, cyano, isocyano or an optionally substituted imine of the formula --CH.dbd.NZ or --N.dbd.CH.sub.2 wherein Z is hydrogen, alkyl, aryl, sulphonyl, --SR.sup.a, sulphoxide --SR.sup.a, or sulphonate --SR.sup.a wherein R.sup.a is alkyl of 1 to 6 carbon atoms or aryl, are useful as intermediates for the ultimate production of penicillins or cephalosporins.

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