Process for preparation of superoxide dismutase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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C12N 902

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active

050875680

ABSTRACT:
A process for producing recombinant human Cu, Zn-superoxide dismutase, which comprises treating a solution of copper-free or copper-deficient recombinant human Cu, Zn-superoxide dismutase with a copper salt in the presence of .beta.-mercaptoethanol.

REFERENCES:
patent: 4742004 (1988-05-01), Hartman et al.
Developments in Biochemistry, 11A, 223 (1980) pp. 223-229.
Biochem. Biophys. Acta, 537, 86 (1978), pp. 86-99.
Patel, In Biotechnology, Applications and Research, eds. Cheremisnoff and Ouellette. Technomic Publishers, Lancaster, PA., 1985, pp. 553-554.

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