Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-03-17
1985-02-12
Milestone, Norma S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
564225, C07D21114, C07C12300
Patent
active
044992742
ABSTRACT:
An improved process for preparing fenoctimine, which is 4-(diphenylmethyl)-1-[(octylimino)methyl]piperidine by: (1) reacting dimethylformamide with dimethyl sulfate to form a complex; (2) reacting the resultant dimethylformamide/dimethyl sulfate complex with n-octylamine and optionally with dimethylamine; (3) thereafter treating the reaction with aqueous base to form N,N-dimethyl-N'-octyl-formamidine; and (4) reacting said formamidine, without need for further purification, with 4-(diphenylmethyl) piperidine to obtain 4-(diphenylmethyl)-1-[(octylimino)-methyl]piperidine.
REFERENCES:
patent: 3971647 (1976-07-01), Gaetzi et al.
patent: 4251655 (1981-02-01), Scott et al.
patent: 4353830 (1982-10-01), Mark
patent: 4448975 (1984-05-01), Mark
H. Bredereck et al., Angew. Chem. Internat. Edit., vol. 1, (1962) No. 6, pp. 331-332.
A. I. Meyers et al., J. Am. Chem. Soc. (1980), vol. 102, pp. 7125-7126.
A. I. Meyers et al., Tetrahedron Letters, vol. 22, No. 51, pp. 5115-5118 (1981).
Roczniki Chemii Ann. Soc. Chim. Polonorum 45, 103 (1971) pp. 103-105.
Feth Georg
Mills John E.
Levy David J.
McNeilab Inc.
Milestone Norma S.
LandOfFree
Process for preparation of substituted formamidine and substitut does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for preparation of substituted formamidine and substitut, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparation of substituted formamidine and substitut will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1390571