Process for preparation of streptovaricin

Details Process for preparation of streptovaricin Process for preparation of streptovaricin

1992-04-29

1993-09-07

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435121, 435124, 435245, 4352536, 435886, C12P 1718, C12P 1708, C12P 1962, C12R 1465

Patent

active

052428150

ABSTRACT:
A method for producing streptovaricin by culturing a streptovaricin producing strain in the presence of a nonionic adsorbent. This procedure substantially increases the production efficiency of the streptovaricin. A second embodiment wherein the streptovaricin producing strain is produced in the presence of fumaric acid or its water soluble salts to provide improvements in production efficiency is also disclosed.

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patent: 5137825 (1992-08-01), Inoue et al.
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K. L. Rinehart Jr., et al. "Relative Biological Activities of Individual Streptovaricins & Acetates", Biochem. vol. 13, No. 5, pp. 861-867 (1974).
K. Sasaki et al. "Chemical Modification of Streptovaricins C", J. Antibiotics vol. 29, No. 2, pp. 147-154 (Feb. 1976).

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