Process for preparation of R-(-)-3-halogeno-1,2,-propanediol by

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435 42, 4352533, 435280, 435874, 435875, 435876, 435877, C12P 718, C12P 4100, C12R 138, C12N 120

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active

052468437

ABSTRACT:
A process for preparation of R-(-)-3-halogeno-1,2-propanediol which comprises cultivating in a medium containing racemate 3-halogeno-1,2-propanediol a bacterium, which, when cultivated in a medium containing racemate 3-halogeno-1,2-propanediol as a sole carbon source, can grow and proliferate, has an ability to assimilate S-(+)-3-halogeno-1,2-propanediol preferentially compared to R-(-)-3-halogeno-1,2-propanediol and belongs to the genus Pseudomonas, or its culture cells; and recovering R-(-)-3-halogeno-1,2-propanediol from the resulting culture broth.

REFERENCES:
patent: 5017484 (1991-05-01), Nakamura et al.

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