Process for preparation of propionic acid

Details Process for preparation of propionic acid Process for preparation of propionic acid

1984-04-03

1988-03-22

Weimar, Elizabeth

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435244, 435801, 435822, C12N 138, C12P 752, C12R 101

Patent

active

047328550

ABSTRACT:
An improved process for the production of propionic acid comprises cultivating a propionic acid-producing bacterium anaerobically in a medium which contains a simple carbohydrate, which can be converted by the bacterium to pyruvate, as well as essential minerals, vitamins, and growth factors under an overpressure of hydrogen which is effective to cause a hydrogenase produced by the bacterium to suppress the oxidation of pyruvate to acetate and carbon dioxide and to promote the formation of propionic acid.

REFERENCES:
patent: 4400470 (1983-08-01), Zeikus et al.
Schink, B., Thompson, T. E. and Zeikus, J. G., (1982), J. Gen. Microbiol., 128, 2771-2779.
Kerby, R., Niemczura, W., and Zeikus, J. G., (1983), J. Bacteriol., 155, 1208-1218.
Zeikus, J. G., Fuchs, G., Kenealy, W., and Thauer, R. K., (1977), J. Bacteriol., 132, 604-613.
Lamed, R. and Zeikus, J. G., (1980), J. Bacteriol., 144, 569-578.
Schink, B., Lupton, F. S. and Zeikus, J. G., (1983), Appl. Environ. Microbiol., 45, 1491-1500.
Zeikus, J. G., (1983), Microbes in Their Natural Environments, Soc. Gen. Microbiol., Cambridge University Press.
Zeikus, J. G., (1980), Ann. Rev. Microbiol., 34, 423-464.

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