Process for preparation of optically pure lactones from monoeste

Details Process for preparation of optically pure lactones from monoeste Process for preparation of optically pure lactones from monoeste

1978-06-30

1980-08-12

Trousof, Natalie

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D30793

Patent

active

042172845

ABSTRACT:
A novel monoester of cis-cyclopentenediol of the following formula ##STR1## wherein ##STR2## is an optically active acyl moiety. The monoester can be prepared by reacting cis-2-cyclopentene-1,4-diol with an optically active carboxylic acid of the following formula ##STR3## wherein ##STR4## is the same as defined above, or its reactive derivative, and separating the resulting reaction product into the two individual diastereomers. Lactones can be prepared from the monoesters selectively and with commercial advantage.

REFERENCES:
patent: 3887606 (1975-06-01), Phillipps et al.
patent: 3904648 (1975-09-01), Kelly
patent: 3970673 (1976-07-01), Kondo et al.
patent: 3976680 (1976-08-01), Clark et al.
patent: 4012429 (1977-03-01), Sakai et al.
patent: 4064351 (1977-12-01), Sakai et al.
Corey et al., Tetrahedron Letters, No. 4, pp. 311-313, 1970.
Corey et al., Tetrahedron Letters, No. 28, pp. 2439-2440, 1974.
Corey et al., Jour. of Amer. Chem. Soc., 91:20, Sep. 1969, pp. 5675-5677.
Kondo et al., Angnew. Chem., Internat. Edit., vol. 14, 1975, No. 2, p. 103.
Partridge et al., Jour. of the Amer. Chem. Soc., 95:21, Oct. 17, 1973.
Mitra, The Synthesis of Prostaglandins, 1977, p. 243, John Wiley & Sons, New York.
Takno et al., Journal of the Chemical Society Chemical Communications, Jun. 1976, pp. 189-190.
Reese, Protective Groups in Organic Chem., Edited by McOmie, 1973, Plenum Press.

Affiliated with

Also associated with

Rating

Process for preparation of optically pure lactones from monoeste does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparation of optically pure lactones from monoeste, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparation of optically pure lactones from monoeste will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2182032