Process for preparation of novel angiotensin II antagonists

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435827, C12R 1045, C12P 1718

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active

050533290

ABSTRACT:
Novel biotransformation compounds I and II are prepared by fermenting 3-[(2'-tetrazol-5-yl-biphenyl-4-yl)methyl]-7-methyl-2-propyl-3H-imidazo[4, 5-b]pyridine in a culture of Actinoplanacete sp., Accession No. ATCC 53771. ##STR1##

REFERENCES:
patent: 4975372 (1990-12-01), Arison et al.
patent: 4981792 (1991-01-01), Inamine et al.
patent: 4987139 (1991-01-01), Chen et al.
patent: 4997849 (1991-03-01), Petuch et al.

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