Process for preparation of L-tryptophan by enzyme

Details Process for preparation of L-tryptophan by enzyme Process for preparation of L-tryptophan by enzyme

1980-04-25

1982-06-15

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435233, 435280, C12P 1322

Patent

active

043352090

ABSTRACT:
A process for the preparation of L-tryptophan comprises reacting indole with serine in the presence of tryptophan synthetase or tryptophanase, wherein DL-serine or D-serine is used and a serine racemizing enzyme is included in the reaction system and reacted with the serine.

REFERENCES:
patent: 3929573 (1975-12-01), Konosuke et al.
Soda et al., Biochemical and Biophysical Research Communications vol. 35 No. 3 pp. 363-368 (1969).
Osumi, doctoral thesis "Studies on Amino Acid Racemase of Pseudomonas Striata" Kyoto University 1973 (74 pages).
Marconi et al., Agr. Biol. Chem. 38(7), 1343-1349 (1974).
Soda et al., Agr. Biol. Chem. 31(9), 1097-1099 (1967).
Soda et al., Agr. Biol. Chem. 33(3), 424-429 (1969).
Osumi et al., Agr. Biol. Chem. 33(3) 430-435 (1969).

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