Process for preparation of deoxyribonucleases

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435172, C12N 922, C12N 1500

Patent

active

042594464

ABSTRACT:
Disclosed is a process for the preparation of deoxyribonucleases (DNases) which comprise culturing a novel transformant belonging to the genus Bacillus, collecting a cell-free extract from cells obtained during a period ranging from the late logarithmic growth phase to the initial stage of the stationary growth phase, and subjecting said cell-free extract to fractionation or separation to obtain two or more DNases each of which possessing different substrate specificity.

REFERENCES:
patent: 3930956 (1976-01-01), Juni
patent: 4080261 (1978-03-01), Shibata et al.
patent: 4161424 (1979-07-01), Ando et al.

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