Process for preparation of .beta.-lactams utilizing a combined c

Details Process for preparation of .beta.-lactams utilizing a combined c Process for preparation of .beta.-lactams utilizing a combined c

1994-01-18

1996-06-11

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound having a 1-thia-4-aza-bicyclo

435 46, 435 50, C12P 3704, C12P 3702

Patent

active

055254837

ABSTRACT:
.beta.-Lactam derivatives are synthesized by an enzymatic reaction of the parent amino .beta.-lactam with the corresponding acylating agent, the concentration of the acylating agent plus the concentration of .beta.-lactam derivative in the reaction mixture being above about 400 mM.

REFERENCES:
patent: 3079305 (1963-02-01), Kaufmann et al.
patent: 3152050 (1964-10-01), Grant et al.
patent: 4335211 (1982-06-01), Hashimoto et al.

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