Process for preparation of azolylmethylcycloalkanol derivatives

Details Process for preparation of azolylmethylcycloalkanol derivatives Process for preparation of azolylmethylcycloalkanol derivatives

1994-11-10

1995-11-14

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5482672, 5482674, 5482686, 5483355, 5483361, C07D24908, C07D23360

Patent

active

054668166

ABSTRACT:
A process for preparing a derivative of azolylmethylcycloalkanol of the following formula (I) comprising, providing a solid-liquid two-phase mixture of a cycloalkanone derivative of formula (II), an azole compound of formula (III), a metal oxide of formula (IV), and an organic solvent, and adding a sulfonium compound of formula (V) to said solid-liquid two-phase mixture under heating while stirring, ##STR1## wherein R.sup.1 and R.sup.2 individually represent a hydrogen atom or an alkyl group; X is a halogen atom, an alkyl group, a haloalkyl group, a phenyl group, a cyano group, or a nitro group; m is an integer of 0 to 5 (when m is 2 or larger, Xs may be either the same or different); n is an integer of 0 to 2; A represents a nitrogen atom or a group CH; M.sup.1 represents an alkali metal atom or an alkaline earth metal atom; M.sup.2 represents an alkaline earth metal atom, a zinc atom, or two alkali metal atoms; Y represents a halogen atom or a C.sub.1 -C.sub.4 alkoxysulfonyloxy group; and p denotes an integer of 0 or 1.

REFERENCES:
patent: 4670454 (1987-06-01), Janssen et al.
patent: 4938792 (1990-07-01), Kumazawa et al.
patent: 5194444 (1993-03-01), Seele et al.
patent: 5256683 (1993-10-01), Hutt et al.
Y. Izumi et al., "Liquid-Phase Organic Reactions Catalyzed by Inorganic Solid Acids and Bases", Chemical Abstracts 117:654 (1992).

Affiliated with

Also associated with

Rating

Process for preparation of azolylmethylcycloalkanol derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparation of azolylmethylcycloalkanol derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparation of azolylmethylcycloalkanol derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1222101