Process for preparation of aspartylphenylalanine alkyl esters

Details Process for preparation of aspartylphenylalanine alkyl esters Process for preparation of aspartylphenylalanine alkyl esters

1982-08-26

1985-03-19

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using tissue cell culture to make a protein or polypeptide

435829, 435877, 435911, 435944, C12P 2102, C12R 105, C12R 140, C12R 1645, C12R 188

Patent

active

045060118

ABSTRACT:
.alpha.-L-aspartylphenylalanine lower alkyl esters are prepared by a process wherein L-aspartic acid and a lower alkyl ester of L-phenylalanine are contacted with a culture or treated culture product of a microorganism belonging to the genus Pseudomonas, Alcaligenes, Torulopsis, Rhodotorula or Sporobolomyces and being capable of producing a .alpha.-L-aspartyl-L-phenylalanine lower alkyl ester from L-aspartic acid and a lower alkyl ester of L-phenylalanine.

REFERENCES:
patent: 4119493 (1978-10-01), Isowa et al.
patent: 4284721 (1981-08-01), Oyama et al.

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