Process for preparation of amidine derivatives

Details Process for preparation of amidine derivatives Process for preparation of amidine derivatives

2006-01-17

2006-01-17

Desai, Rita (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S089000, C546S153000, C546S159000, C546S160000

Reexamination Certificate

active

06987187

ABSTRACT:
A process for producing amidine derivatives represented by the following reaction scheme, characterized in that the reactions of steps 1 and 3 are conducted in acetonitrile and the reaction of step 2 is conducted in acetone.

REFERENCES:
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Volovenko et al, Chem. Abs. vol. 117 No. 233799, “Synthesis and biological activity of alpha sub. 2-pyridylacetonitirl;es” (1992) (Best Available).
M. Adachi et al., “Intermolecular transfer of an alkenyl group in enamines: application to synthesis of [b]-fused pyridins”, Tetrahedron Letters, 1996, vol. 37, No. 49, pp. 8871-8874.
M. Dolezal et al., “Synthesis and antimycobacterial, antigungal, and photosynthesis-inhibiting evaluation of some anilides of substituted pyrazine-2-carboxylic acids”, Chemical Papers, 2000, vol. 54, No. 4, pp. 245-248.
M. Adachi et al., “Intermolecular transfer of an alkenyl group in enamines: application to synthesis of [b]-fused pyridins”, Tetrahedron Letters, 1996, vol. 37, No. 49, pp. 8871-8874.
M. Dolezal et al., “Synthesis and antimycobacterial, antigungal, and photosynthesis-inhibiting evaluation of some anilides of substituted pyrazine-2-carboxylic acids”, Chemical Papers, 2000, vol. 54, No. 4, pp. 245-248.

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