Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1989-12-08
1990-08-28
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
562466, 562469, 562463, C07C 5948, C07C 6206, C07C 5990
Patent
active
049527240
ABSTRACT:
A process for producing aryloxy acetic acids and salts thereof which comprises reacting an alcohol of the formula R-OH wherein R is aryl or substituted aryl with a base in an aprotic organic solvent to give an aryloxide followed by removal of the organic solvent and reaction of the aryloxide with a salt of a monohaloacetic acid in a polar aprotic solvent such as DMSO to give the corresponding aryloxyacetate salt which then may be recovered or may optionally be converted to the corresponding acid by contacting the aryloxyacetate salt with an acid.
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Fuson, et al., Organic Synthesis Collected Volumes, 2: 260-262 (1943).
Campbell Arthur L.
Mueller Richard A.
Ng John S.
Partis Richard A
G. D. Searle & Co.
Kanady Mary Jo
Killos Paul J.
Matukaitis Paul D.
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