Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-05-02
2006-05-02
Solola, Taofiq (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C549S528000
Reexamination Certificate
active
07038040
ABSTRACT:
Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of Formula Iwherein:-A-A- represents the group —CHR4—CHR5— or CR4═CR5—R3, R4and R5are independently selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl, lower alkoxy, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, cyano, aryloxy,R1represents an alpha-oriented lower alkoxycarbonyl or hydroxyalkyl radical,-B-B- represents the group —CHR6—CHR7— or an alpha- or beta-oriented group: where R6and R7are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, andR8and R9are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano, aryloxy, or R8and R9together comprise a carbocyclic or heterocyclic ring structure, or R8or R9together with R6or R7comprise a carbocyclic or heterocyclic ring structure fused to the pentacyclic D ring.
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Anderson Dennis K.
Baez Julio A.
Erb Bernhard
Kunda Sastry A.
Lawson Jon P.
Ashbrook Charles
G.D. Searle & Co.
Solola Taofiq
Thomas Robert S.
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