Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2008-01-08
2008-01-08
Puttlitz, Karl (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C562S567000, C564S199000
Reexamination Certificate
active
10482946
ABSTRACT:
The invention relates to novel synthesis methods for the preparation of the intermediates, which are suitable for the preparation of statin derivatives, especially to novel synthesis methods of the intermediate of formula VI wherein Ra′ and Rc′ are each independently of the other hydrogen or a hydroxy-protecting group or together are a bridging hydroxy-protecting group, and Rbis a carboxy-protecting group, which methods are carried out by conversion of the intermediate of formula XVI wherein Ra′ and Rc′ are each independently of the other hydrogen or a hydroxy-protecting group, R* and R** are each independently of the other hydrogen or an amide-protecting group, and Rbis a carboxy-protecting group; which methods proceed to further new intermediates and methods for their preparation
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Baisch Gabriele
Bienewald Frank
Burkhardt Stephan
Kirner Hans Jörg
Öhrlein Reinhold
Kenyon & Kenyon LLP
Puttlitz Karl
Teva Pharmaceutical Industries Ltd
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