Process for preparation of 13-cis-retinoic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...

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20415764, C07C 51353, C11C 314

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active

058920730

ABSTRACT:
Photochemical isomerization of 11-cis-, 13-cis-retinoic acid to 13-cis-retinoic acid characterized in that it is performed in an aqueous solution of an alkaline salt of said 11-cis-, 13-cis-retinoic acid.

REFERENCES:
patent: 4556518 (1985-12-01), Lucci
patent: 5424465 (1995-06-01), John et al.
European Search Report, Sep. 4, 1997, Examiner Bonnevalle, E.
J. Chem. Soc. 1984 (1964); "Carotenoids and Related Compounds, Part XVIII..sup.1 Synthesis of Cis- and Di-Cis-Polyenes by Reactions of the Witting Type", by Gerald Pattenden and B.C.L. Weedon.

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