Process for precipitating aminoglycosides

Details Process for precipitating aminoglycosides Process for precipitating aminoglycosides

1980-02-04

1981-03-17

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 9, 536 10, 536 17A, 536 17R, C07H 106

Patent

active

042568765

ABSTRACT:
A highly efficient process for the precipitation of an amorphous (non-crystalline) aminoglycoside antibiotic salt during the purification process. Illustratively, there are disclosed processes for precipitating gentamicin, neomycin, and sisomicin salts.

REFERENCES:
patent: 2799620 (1957-07-01), Waksman et al.
patent: 3091572 (1963-05-01), Luedemann et al.
patent: 3651042 (1972-03-01), Marquez et al.
Rosselet et al., "Antimicrob. Agents & Chemotherapy", pp. 14-16, 1963.
Wagman et al., "The Jour. of Antibiotics", vol. 23, pp. 555-558, 1970.
Korzeniowski et al., "Principles and Practice of Infectious Disease", G. L. Mandell et al. (Eds.), Wiley & Sons, N. Y. 1979, pp. 249-251 & 268.

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