Process for oxidizing primary alcohols

Details Process for oxidizing primary alcohols Process for oxidizing primary alcohols

2005-08-30

2005-08-30

Wilson, James O. (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S018500, C536S018600, C536S018700, C536S045000, C536S056000, C536S063000, C536S102000, C536S105000, C536S123000, C536S123100

Reexamination Certificate

active

06936710

ABSTRACT:
Primary hydroxyl groups in a substrate having both primary and secondary hydroxyl groups can be selectively oxidized to carbaldehyde and/or carboxyl groups by contacting the substrate with a cyclic nitroxyl compound in the presence of a peroxosulfate as a co-oxidant and by carrying out the reaction at a temperature below 30° C. and at a pH below 9. The process is halogen-free and metal-free and is especially suitable for oxidizing polysaccharides.

REFERENCES:
patent: 6310200 (2001-10-01), Vermaas
patent: 1 086 938 (2001-03-01), None
patent: 95/07303 (1995-03-01), None
patent: 96/38484 (1996-12-01), None
patent: 99/57158 (1999-11-01), None
patent: 01/00681 (2001-01-01), None
Bolm C., et al.,“Catalytic Synthesis of Aldehydes and Ketones Under Mild Conditions Using TEMPO/Oxone”,Org. Lett. ACS,(Published on Web) 2(8) 1173-1175, 2000.
Brik, M. E., “Oxidation of Secondary Amines to Nitroxides with Oxone in Aqueous Buffered Solution”,Tetrahedon Lett.,(Elsevier Science LTD) 36 (31):5519:5522, 1995.
Davis, N. J. and Flitsch, S. L., “Selective Oxidation of Monosaccharide Derivatives to Uronic Acids”,Tetrahedron Lett.(Pergamon Press Ltd) 34(7): 1181-1184, 1993.
Kochkar, H., et al., “Regioselective Oxidation of Hydroxyl Groups of Sugar and its Derivatives Using Silver Catalysts Mediated by TEMPO and Peroxodisulfate in Water”,J. Catalysis,(American Press) 194(2): 343-351, 2000.

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