Process for optically pure decahydroisoqiunolines

Details Process for optically pure decahydroisoqiunolines Process for optically pure decahydroisoqiunolines

1992-11-09

1995-01-10

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21700

Patent

active

053808495

ABSTRACT:
A process for preparing optically pure decahydroisoquinolines in good yields which avoids difficult purification procedures is described.

REFERENCES:
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patent: 4902695 (1990-02-01), Ornstein
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Krishnbamarthy, S., ". . . N-Monomethylation of Functionalized Primary Amines . . . ," Tetrah. Lett. 23, 3315 (1982).
Ornstein, P. L. et al., ". . . 6-Oxodecahydroisoquinoline-3-carboxylates . . . ," J. Org. Chem. 56, 4388 (1991).
Lipton M. F. et al.,". . . Dimethylaluminum amides . . . ," Organic Synth., 59, 49 (1978).
Stork, G. et al., "Alkylation and Michael Additions of Glycine Ethyl Ester . . . ," J. Org. Chem. 41, 3491 (1976).
Shiraiwa, T. et al., "Asymmetric Transformation . . . ," Bull. Chem. Soc. 64, 3729 (1991).
Hayashi, K. et al., "Facile Preparation . . . ," Chem. Pharm. Bull. 31, 312 (1983).

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