Process for optically active 3-thiolanyl sulfonate esters

Details Process for optically active 3-thiolanyl sulfonate esters Process for optically active 3-thiolanyl sulfonate esters

1989-07-12

1990-05-01

Siegel, Alan

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D33332

Patent

active

049219723

ABSTRACT:
Intermediates and a stepwise process for the conversion of an alkyl 4-chloro-3R-hydroxybutyrate to optically active compounds of the formula ##STR1## wherein R is (C.sub.1 -C.sub.3)alkyl, phenyl or tolyl. The latter compounds are in turn useful as an intermediate in the preparation of penem antibiotic 5R,6S-6-(1R-hydroxyethyl)-2-(1R-oxo-3S-thiolanylthio)-2-penem-3-carboxylic acid and corresponding pharmaceutically acceptable salts and esters.

REFERENCES:
patent: 2581443 (1952-01-01), Reynolds
patent: 2726162 (1955-12-01), Allen
patent: 3041241 (1962-06-01), Timmis

Affiliated with

Also associated with

Rating

Process for optically active 3-thiolanyl sulfonate esters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for optically active 3-thiolanyl sulfonate esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for optically active 3-thiolanyl sulfonate esters will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-830817