Process for obtaining pure L-leucine

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...

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435280, C12P 1306, C07P 4100

Patent

active

045621527

ABSTRACT:
Pure L-leucine is obtained from an aminoacid mixture which contains at least 45 weight percent L-leucine, at most 40 weight percent L-isoleucine and at most 25 weight percent of other aminoacids by acetylating the mixture, precipitating the acetylation product by acidification, subjecting the acetylation product to a saponification by an L-aminoacid acylate until 30 to 95% of the N-acetyl-L-leucine employed is saponified and isolating the L-leucine from the saponification mixture.

REFERENCES:
patent: 3841966 (1974-10-01), Soichiro et al.
patent: 4259441 (1981-03-01), Bauer

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