Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1996-11-15
1998-12-08
Lankford, Jr., Leon B.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530395, 530412, 530415, 530417, 536 20, 536 21, A61K 3514, C08B 3708, C08B 3710
Patent
active
058470840
ABSTRACT:
The present invention, using a readily available sulfated chitin as an adsorbent, can permit platelet factor-4 to be recovered through specific adsorption from a solution containing the same factor, in by far increased yields as compared with the conventional process utilizing a heparin-immobilized affinity column, and provides the process for isolating, through purification platelet factor-4 which is suited for a commercial-scale, mass production process, wherein there can be offered the advantages of utilization of more readily available sulfated chitin, simplified procedure and improved production yields for the objective substance.
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Hirose Takashi
Koh Keihide
Komurasaki Yoshikazu
Nishimuro Satoshi
Shindoh Chihiro
JCR Pharmaceuticals Co. Ltd.
Lankford , Jr. Leon B.
Tate Christopher R.
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