Process for obtaining P-acetamido phenol .alpha.-methyl-4(2'thie

Details Process for obtaining P-acetamido phenol .alpha.-methyl-4(2'thie Process for obtaining P-acetamido phenol .alpha.-methyl-4(2'thie

1981-11-23

1982-10-05

Siegel, Alan

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424275, C07D33316, A61K 3138

Patent

active

043529356

ABSTRACT:
Para-acetamidophenol .alpha.-methyl-4(2'-thienyl-carbonyl) phenyl acetate, having anti-inflammatory activity, is provided, along with a process for its preparation by reacting .alpha.-methyl-4(2'-thienyl-carbonyl) phenyl acetic acid or a reactive species thereof with p-acetamidophenol in an aprotic organic solvent and, when the reactive species is an acid halide, the reaction is carried out also in the presence of a hydrohalic binding compound.

REFERENCES:
patent: 3903114 (1975-09-01), Martret et al.
patent: 4064132 (1977-12-01), Janssen et al.
patent: 4153718 (1979-05-01), Goudie
patent: 4159986 (1979-07-01), Clemence et al.

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