Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Insulin; related peptides
Patent
1998-08-17
1999-11-16
Moezie, F. T.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Insulin; related peptides
530324, A61K 3828
Patent
active
059860480
ABSTRACT:
The present invention relates to an improved process for obtaining a precursor of an insulin or insulin derivative having correctly bonded cystine bridges in the presence of cysteine or cysteine hydrochloride and chaotropic auxiliary.
REFERENCES:
patent: 4801684 (1989-01-01), Grau
patent: 5473049 (1995-12-01), Obermeier et al.
patent: 5663291 (1997-09-01), Obermeier et al.
Keller Reinhold
Rubroder Franz-Josef
Hoechst Marion Roussel Deutschland
Moezie F. T.
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