Process for obtaining insulin precursors having correctly bonded

Details Process for obtaining insulin precursors having correctly bonded Process for obtaining insulin precursors having correctly bonded

1998-08-17

1999-11-16

Moezie, F. T.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Insulin; related peptides

530324, A61K 3828

Patent

active

059860480

ABSTRACT:
The present invention relates to an improved process for obtaining a precursor of an insulin or insulin derivative having correctly bonded cystine bridges in the presence of cysteine or cysteine hydrochloride and chaotropic auxiliary.

REFERENCES:
patent: 4801684 (1989-01-01), Grau
patent: 5473049 (1995-12-01), Obermeier et al.
patent: 5663291 (1997-09-01), Obermeier et al.

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