Process for obtaining genistin malonate and daidzin malonate

Details Process for obtaining genistin malonate and daidzin malonate Process for obtaining genistin malonate and daidzin malonate

1990-10-16

1992-08-25

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

514 25, 549403, 424 7803, 426133, A61K 3578, A01N 4304

Patent

active

051417464

ABSTRACT:
Genistin and daidzin malonates are obtained by extracting ground soya bean with methanol or ethanol to obtain an extract. The extract is buffered to a pH of 6 to 9 and then extracted with a water-immiscible solvent. The aqueous phase is recovered, acidified to a pH of 2 to 5.4, and then extracted with a water-immiscible solvent. The organic phase is recovered, neutralized to a pH of 6.8 to 7.2, and the malonates are separated therefrom.

REFERENCES:
patent: 4163746 (1979-08-01), Feuer
patent: 4166862 (1979-09-01), Feuer
patent: 4428876 (1984-01-01), Iwamura
patent: 4524067 (1985-06-01), Arichi et al.
patent: 4557927 (1985-12-01), Miyake
patent: 4963527 (1990-10-01), Bombardelli

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