Process for obtaining chemically defined and reproducible polyde

Details Process for obtaining chemically defined and reproducible polyde Process for obtaining chemically defined and reproducible polyde

1992-05-26

1993-06-29

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 91, C07N 100

Patent

active

052236099

ABSTRACT:
Depolymerization of stabilized solutions of highly polymerized and nicked polydeoxyribonucleotides, as obtained through stabilizing aggregation of raw nucleic acids, the depolymerization being carried out by heating at controlled temperature and being controlled as a function of the variation of the reversible hyperchromicity, followed by the removal of the hydrogen bonds in the double stranded filaments and by thermal stabilization of the single stranded filaments, polydeoxyribonucleotide is obtained. The polydeoxyribonucleotide has the following formula of random sequence:

REFERENCES:
patent: 3829567 (1974-08-01), Butti et al.
patent: 3899481 (1975-08-01), Butti et al.
patent: 4649134 (1987-03-01), Bonomini et al.

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