Process for obtaining agents having mitogenic and/or adjuvant pr

Details Process for obtaining agents having mitogenic and/or adjuvant pr Process for obtaining agents having mitogenic and/or adjuvant pr

1977-03-28

1980-05-06

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424195, A61K 3902, A61K 3574

Patent

active

042017688

ABSTRACT:
The invention relates to a process for obtaining agents having mitogenic and/or adjuvant properties, from Nocardia cells.
According to this process Nocardia whole cells are subjected to a rupturing treatment of their walls within an aqueous medium, particularly distilled water. After the separation of the non-ruptured cells and of the wall fragments of the ruptured cells, mitogenic agents are extracted from the remaining aqueous phase. The fractions obtained are useful as laboratory reagents and for the production of medicamentous compositions in which they are associated with a pharmaceutical vehicle.

REFERENCES:
Constantin et al.,-Chem. Abst., vol. 81, (1974), p. 45982k.
Adam et al.,-Chem. Abst., vol. 79, (1973), p. 30388f.
Petit et al.,-Chem. Abst., vol. 79, (1973), p. 64476y.
Adam et al.,-Chem. Abst., vol. 85, (1976), p. 121690p.
Ciorbaru et al.-Chem. Abst., vol. 84, (1976), p. 41997h.
Bona et al.,-Chem. Abst., vol. 82, (1975), p. 123134x.
Azuma et al.-Chem. Abst, vol. 80, (1974), 124749x.
Azuma et al.-Chem. Abst., vol. 83, (1975), p. 6891b.

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