Process for N-desmethylating erythromycins and derivatives there

Details Process for N-desmethylating erythromycins and derivatives there Process for N-desmethylating erythromycins and derivatives there

1997-11-19

1999-03-16

Peselev, Elli

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 185, G07H 100

Patent

active

058832360

ABSTRACT:
Disclosed is an improved and efficient process for N-desmethylating the 3'-amino nitrogen of erythromycins and for converting the 3'-N-desmethylated erythromycins into 3'-N-substituted derivatives of 8,9-anhydro-erythromycin 6,9-hemiketals.

REFERENCES:
patent: 3726385 (1973-04-01), Freeberg
patent: 5578579 (1996-11-01), Lartey et al.

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