Process for manufacturing fibrin membranes and fibrin...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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Details

C530S381000, C530S382000, C424S484000, C424S529000, C424S530000

Reexamination Certificate

active

07348411

ABSTRACT:
A process for manufacturing a fibrin membrane from blood plasma that was partially depleted and subjected to coagulation by adding a solution of a physiological coagulating agent, leaving the mixture to stay until forming a gelatinous blood clot, and then dehydrating said blood clot to obtain a fibrous membrane, which is subjected to washing with softening agents and then to drying until obtaining a flexible and mouldable membrane. The membrane so obtained is capable to provide an immediate and complete haemostasis, followed by a whole reabsorption, without risk of adhesions with the neighboring tissues, up to the cicatrisation of the injured tissue. The membrane is mouldable and elastic, and is provided with high mechanical properties. It may be soaked with disinfectant agents, drugs or tissue growth factors.

REFERENCES:
patent: 4427651 (1984-01-01), Stroetmann
patent: 6368298 (2002-04-01), Beretta et al.
patent: 2002/0131933 (2002-09-01), Delmotte
patent: 52 156912 (1977-12-01), None
patent: WO 98/58689 (1998-12-01), None

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