Process for manufacturing effervescent granules and tablets and

Details Process for manufacturing effervescent granules and tablets and Process for manufacturing effervescent granules and tablets and

1987-07-10

1989-10-10

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Gas produced in situ by chemical reaction

34 63, 34 65, 34 92, 25218312, 25218313, 252350, 2523635, 514163, 514474, 514629, 514960, 514961, A61L 904, B01F 312, C06D 510, F26B 1712

Patent

active

RE0330868

ABSTRACT:
The invention relates to a process for manufacturing effervescent tablets consisting in the steps of careful humidifying of the acid+base mixture, pre-drying and final drying and granulating.
It has been found that these operations can be performed in a single apparatus, either integrally in fluid bed, or with vacuum-drying.

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Lieberman et al., "Pharmaceutical Dosage Forms: Tablets", vol. 3, pp. 34-37 (1982).
Bartsch, "Die Pharmazeutische Industrie", vol. 41, pp. 696-698 (1979).

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