Process for manufacturing .alpha..sub. 1L-adrenoceptor antagonis

Details Process for manufacturing .alpha..sub. 1L-adrenoceptor antagonis Process for manufacturing .alpha..sub. 1L-adrenoceptor antagonis

1999-03-24

2000-12-05

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23946, C07D23954

Patent

active

061568945

ABSTRACT:
A process is useful for making compounds of the formula: wherein R is hydro, methyl, or fluoro.
Valuable intermediates in this process include: ##STR1## wherein R is hydro, methyl, or fluoro, and L is a leaving group.

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Greene, T. W., Protective Group in Organic Synthesis, pp. 284-287, 1981.
Marturisyan et al. Izv.Akad. Nauk SSSR, Ser. Khim. 5, 1127-31, 1970.
Martirosyan et al. Izv.Akad. Nauk SSSR, Ser. Khim. 8, 184-4, 1970.
Chem. Abstract, vol. 73, No. 13, No. 66534r, 1970.
Chem. Abstract, vol. 74, No. 33, No. 54134t, 1970.
Kasnar, B.; et al., Nucleosides & Nucleotides, 16, pp. 1067-1071 (1997).

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