Process for making topotecan

Details Process for making topotecan Process for making topotecan

2011-07-12

2011-07-12

Aulakh, Charanjit S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S047000

Reexamination Certificate

active

07977483

ABSTRACT:
A process of making topotecan or a pharmaceutically acceptable salt thereof comprising reacting an iminium salt with 10-hydroxy-camptothecin.

REFERENCES:
patent: 5004758 (1991-04-01), Boehm et al.
patent: 5734056 (1998-03-01), Burk et al.
patent: 6660861 (2003-12-01), Puri et al.
patent: 7547785 (2009-06-01), Palle et al.
patent: WO/2005046608 (2005-05-01), None
L.A. Paquett: “Encyclopedia of reagents for organic synthesis” Jan. 1, 1995, vol. 3, p. 2090-2093. XP-002575696.
Chen et al., Studies on the polymorph of topotecan hydrochloride and its stability In: Zhongguo Shenghua Yaowu Zazhi, 2005, 26(5), p. 279-281.
Vogt et al., A study of variable hydration states in topotecan hydrochloride In: Journal of Pharmaceutical and Biomedical Analysis, 2006, 40(5), p. 1080-1088.

Affiliated with

Also associated with

Rating

Process for making topotecan does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for making topotecan, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for making topotecan will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2699058