Process for making porous membranes

Plastic and nonmetallic article shaping or treating: processes – Pore forming in situ

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264310, 264330, 26433111, 26433119, 427 2, 427245, B05D 500, B29C 4108, B29C 6720

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052290450

ABSTRACT:
Porous, distensible, gel-like membranes which in tubular form are suitable as implants, e.g., vascular prostheses and a process for the preparation thereof. The membranes are formed by a spraying, phase-inversion technique which employs thermodynamically unstable polymer solutions and is accomplished by separately spraying the unstable solution and a nonsolvent onto a rotating surface. Prostheses from the highly porous tubular membranes have shown a high degree of patency and completeness of the healing process and are useful for direct implantation in the body or for extracorporeal vascular accesses.

REFERENCES:
patent: 4770664 (1988-09-01), Gogolewski
patent: 4834747 (1989-05-01), Gogolewski
White, R. A. et al. "Replamineform: A New Process for Preparing Porous Ceramic, Metal and Polymer Prosthetic Materials", Science, vol. 176 (May 26, 1972), pp. 922-924.
Lyman, D. J. et al. "Development of Small Diameter Vascular Prostheses", Transactions of the American Society of Artificial Internal Organs, vol. 23 (1977), pp. 253-260.
Leider, J. et al. "A Novel Process for the Manufacturing of Porous Grafts: Process Description and Product Evaluation", Journal of Biomedical Materials Research, vol. 17 (1983), pp. 229-247.
Kowligi, R. R. et al. "Fabrication and Characteristics of Small-Diameter Vascular Prostheses", Journal of Biomedical Materials Research, vol. 22 (1988), pp. 245-256.
Okoshi et al. Asaio Transactions, vol. 37, No. 3 Jul.-Sep. 1991, publication date Sep. 26, 1991.

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