Process for making optically active α-amino ketones...

Details Process for making optically active α-amino ketones... Process for making optically active α-amino ketones...

2005-02-01

2005-02-01

Killos, Paul J. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C560S125000, C560S170000, C562S451000, C562S567000

Reexamination Certificate

active

06849756

ABSTRACT:
The invention includes selected novel optically active α-amino ketones which either are themselves useful or are intermediates for the preparation of known ketomethylene pseudopeptides useful as antibiotics, antibiotic enhancers, or enzyme inhibitors. Further, the present invention provides a method for dehydrogenation/asymmetrical hydrogenation to obtain essentially pure antipodes of ketomethylene pseudopeptides having two chiral centers.

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