Process for making model skin

Details Process for making model skin Process for making model skin

1989-08-29

1991-05-14

Thurlow, Jeffery

Plastic and nonmetallic article shaping or treating: processes

With step of making mold or mold shaping, per se

Utilizing surface to be reproduced as an impression pattern

264225, 264DIG30, 425 2, B29C 3902

Patent

active

050154311

ABSTRACT:
A process for making a model skin surface for testing adhesion of medical adhesive as a screening test and/or as an alternative to costly and highly variable human skin substrates including casting silicone rubber on human skin to produce a mold having human skin topography and pouring a water-swellable, water-soluble proteinaceous material along with a crosslinking agent and fatty acid constituent into the mold. The proteinaceous material crosslinks while in the mold and the water content of the material is adjustable to simulate varying moisture contents in human skin.

REFERENCES:
patent: 3655416 (1972-04-01), Vinson et al.
patent: 4260574 (1981-04-01), Macomson
patent: 4448718 (1984-05-01), Yannas et al.
patent: 4481001 (1984-11-01), Graham et al.
patent: 4774957 (1988-10-01), Nambu et al.
patent: 4882162 (1989-11-01), Ikada et al.
"Tissue Mimicking Materials For Ultrasound Phantoms", Medical Physics, 5(5), Sep. 1978, pp. 391-391.

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