Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1995-06-07
1999-12-28
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 264 43, 4284022, A61K 9127
Patent
active
060078383
ABSTRACT:
A process for making a liposome preparation comprised of liposomes that contain an encapsulated material is disclosed. The process comprises (A) providing a plurality of portions of a lipid or liposome formulation; (B) hydrating each of the plurality of portions with a solution comprising a material to be encapsulated; and (C) combining each of the plurality of portions to form a single liposome preparation. The liposome preparations can be used for drug delivery or as vaccines.
REFERENCES:
patent: 5607692 (1997-03-01), Ribier et al.
Conrad et al. "The Influence of Retinal on Complement-Dependent Immune Dae to Liposomes," Biochimica et Biophysica Acta, 332: 36-46 (1974).
Alving et al. "Novel Vaccines and Adjuvants: Mechanisms to Action," Aids Research and Human Retroviruses 10(2): 591-594 (1994).
Wassef et al. "Liposomes as Carriers for Vaccines," Immunomethods 4: 217-222 (1994).
Mayhew et al. "Therapeutic Applications of Liposomes," in Liposomes 7: 289-341 (1983).
Alving et al. "Preparation and Use of Liposomes in Immunological Studies," Liposome Technology (2nd Ed.) vol. III (1993) pp. 317-343.
L. S. Rao "Preparation of Liposomes on the Industrial Scale: Problems and Perspectives," in Liposome Technology, vol. I, G. Gregordias, Ed. (1984) pp. 247-257.
Alving Carl R.
Owens Roberta R.
Wassef Nabila M.
Harris Charles H.
Kishore Gollamudi S.
Moran John Francis
The United States of America as represented by the Secretary of
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