Process for making L-aminoacylase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435 712, 435212, 435219, 435227, 435233, 4352521, 435829, C12N 984, C12N 948, C12N 978, C12R 105

Patent

active

051943832

ABSTRACT:
A process for making L-aminoacylase includes a cultivation of microorganism selected from a specy of Alcaligenes, especially the Alcaligenes denitrificans DA 181, and a separation of a produced L-aminoacylase from the bacterial cells for obtaining the L-aminoacylase which may be further purified for the production of L-amino acid. The acylase made by such a process may have an increased stability, beneficial for its commercial and medical values.

REFERENCES:
patent: 4981799 (1991-01-01), Takahashi et al.
Tosa et al., Agr. Biol. Chem., vol. 33, 1047-1052 (1969).
Tosa et al., Agri. Biol. Chem., vol. 33, 1052-1059 (1969).

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