Process for making D-aminoacylase

Details Process for making D-aminoacylase Process for making D-aminoacylase

1991-10-17

1993-04-27

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435 711, 435195, 435227, 435829, C12R 105, C12N 980, C12N 978

Patent

active

052061620

ABSTRACT:
A process for making D-aminoacylse includes adding 1% N-acetyl-DL-amino acid preferably N-acetyl-DL-methionine and N-acetyl-DL-leucine in a culturing medium incubated with bacteria selected from the strain of Alcaligenes faecalis for culturing the bacteria and for inductively promoting an enzyme reaction to produce the D-aminoacylase which is able to hydrolyze D-amino acids and unable to hydrolyze L-amino acids.

REFERENCES:
patent: 4981799 (1991-01-01), Takahashi et al.
Sugie, et al., "Purification and properties, . . . ", (1978), pp. 107-113, Agric. Bio. Chem. 42(1).
Kubo, et al., "Deacetylation of PS-5, . . . ", (Jun. 1980), pp. 556-565 Journal of Antibiotics.
Yang et al., "Purification and Characterization of . . . ", Applied and Environmental Microbiology, vol. 57, No. 4, pp. 1259-1260 USA Apr. 1991.

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