Process for making cyclic imides

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20948

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060374764

ABSTRACT:
A process of producing cyclic imides from cyclic anhydrides is described. Despite the fact that an acid anhydride is reacted with a primary amine in the presence of both water and an acid, the reaction is materially unaffected by acid-catalyzed hydrolysis of the anhydride. Thus a reaction is provided which eliminates the handling and processing problems associated with performing reactions under anhydrous conditions, and which can provide a product of high purity in very high yield.

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