Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus esters
Patent
1969-02-05
1987-10-06
Terapane, John F.
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus esters
C07F 902
Patent
active
H00003468
ABSTRACT:
The compounds of S-(2-dialkylaminoalkyl) alkyl phosphonothioic acids and hod of preparing said compounds possessing anticholinesterase activity comprising an aqueous solution which comprises dialkylaminoalkyl chloride salts which are converted to their corresponding dialkylmonoalkyl ammonium ions and alkylphosphonothioic acids forming a reaction mixture. The latter mixture is placed on a cation exchange resin with subsequent addition of water as an eluting agent giving rise to fractions containing the desired compounds.
REFERENCES:
patent: 2922739 (1960-01-01), Snyder
patent: 3014943 (1961-12-01), Schegk et al.
patent: 3223754 (1965-12-01), Colln et al.
patent: 3480698 (1969-11-01), Cyba
patent: 3501557 (1970-03-01), Brois
patent: 3781387 (1973-12-01), Ford-Moore et al.
patent: 3903210 (1975-09-01), Epstein et al.
Tammelin, "Acta Chemica Scandinavica", 11, 1340-1349 (1957).
Hoffmann et al., J. Am. Chem. Soc., 80, 3945-3948, (1958).
Calderbank et al., J. Chem. Soc., 637-642 (Feb. 1960).
Callahan John J.
Epstein Joseph
Fleisher Joseph H.
Jandorf Bernard J.
Michel Harry O.
Card, Jr. Harold H.
Costigan Edward F.
Lane Anthony T.
Mallon Mary Lou
Terapane John F.
LandOfFree
Process for making compounds possessing anticholinesterase activ does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Process for making compounds possessing anticholinesterase activ, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for making compounds possessing anticholinesterase activ will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2109404