Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Patent
1997-08-18
2000-09-12
Nutter, Nathan M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
530840, 525 541, 623 11, 623 12, 623900, 623901, A61K 3817, A61F 202
Patent
active
061179795
ABSTRACT:
Bioprosthetic devices made of collagen-based material having collagen amine groups and collagen carboxyl groups are provided as well as methods for their formation. The methods comprise combining an epoxy functionalized crosslinking agent with the collagen-based material in an aqueous medium at an acidic pH to react a portion of the collagen carboxyl groups with the epoxy functionalized crosslinking agent to form crosslinked collagen-based material comprising residual collagen carboxyl groups.
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Cahalan Patrick
Dijkstra Piet
Feijen Jan
Hendriks Marc
Verhoeven Michel
Jaro Michael J.
Medtronic Inc.
Nutter Nathan M.
Patton Harold
Woods Thomas F.
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