Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Scleroproteins – e.g. – fibroin – elastin – silk – etc.
Patent
1997-08-18
2000-12-26
Cintins, Marianne M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Scleroproteins, e.g., fibroin, elastin, silk, etc.
530402, 525 541, 8 9411, 623 1, 623 2, 623 3, 623 11, 523113, C07K 1300, C07K 1500
Patent
active
061661848
ABSTRACT:
Methods for making bioprosthetic devices made of collagen-based material having collagen amine groups and collagen carboxyl groups are provided. The methods include blocking at least a portion of the collagen amine groups with a blocking agent, activating at least a portion of the collagen carboxyl groups after blocking at least a portion of the collagen amine groups to form activated carboxyl groups, and contacting the activated collagen carboxyl groups with a polyfunctional spacer to crosslink the collagen-based material.
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Cahalan Linda
Cahalan Patrick
Fouache Benedicte
Hendriks Marc
Michel Verhoeven
Cintins Marianne M.
Delacroix-Muirheid C.
Jaro Michael J.
Medtronic Inc.
Patton Harold
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