Process for making 9-deoxotaxane compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07C30514

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056167407

ABSTRACT:
Process of making compounds having the formula ##STR1## wherein --OR.sup.1 comprises alkanoyl or the C-13 side-chain of taxol; R.sup.2, R.sup.3, and R.sup.6 can be oxygenated or hydrogen in various combinations; and R.sup.4 and R.sup.5 are acyl groups.

REFERENCES:
patent: 4876399 (1989-10-01), Holton et al.
patent: 5015744 (1991-05-01), Holton et al.
Zewert, T. E., et al., "Environment of the Heme in Myoglobins. NMRD and EPR Spectroscopy of Val68X (X-Asn, Asp, and Glu) Mutants of Human Myoglobin" J. Am. Chem. Soc. (1994) vol. 116, No. 4, pp. 1599-1600.

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