Process for making 5-trifluoromethyl pyridone

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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2603435, 26034791, C07D21304

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active

042308640

ABSTRACT:
The chemical compound 5-trifluoromethyl-2-pyrone and a process for preparing a 5-trifluoromethyl-2-oxy compound of the formula ##STR1## wherein A is oxygen or nitrogen bearing a hydrogen, comprising the step of reacting an amount of the 5-carboxy precursor of the compound with a suitable fluorinating agent to selectively transform the 5-carboxy group without altering the oxygen function in the 2-position of the ring.

REFERENCES:
Hudlicky, Chemistry Of Organic Fluorine Compounds, Sec. Edition, John Wiley & Sons, Pub. p. 158, (1976).

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