Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1999-11-18
2000-11-07
Ramsuer, Robert W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544 60, 544295, 5483714, C07D40114
Patent
active
061438928
ABSTRACT:
This invention relates to a novel process of preparing selected 5-substituted pyrazoles useful as p38 kinase and COX-2 inhibitors.
REFERENCES:
Katagiri, N.; Synthesis of Nucleosides and Related Compounds . . . ; Chem. Pharm. Bull. 1990, 12, 3242-3248.
Okajima, N.; Synthesis of Tiocarbonyl and Heterocyclic Compounds from 2-Methylene-1; . . . ; J. Heterocyclic Chem. 1990, 27, 567-574.
Huang, Z. N.; Synthesis of 5-Mercaptoalkylthiopyrazolyl . . . , Synth. Commun. 1996, 26, 3115-3120.
Huang, Z. H.; Synthesis of 5-Mercaptoalkylamino- and . . . Heterocycles 1995, 41, 1653-1658.
Brown David L.
Graneto Matthew J.
Hartmann Susan J.
Metz Suzanne
Stealey Michael A.
G. D. Searle & Co.
Ramsuer Robert W.
Scrivner Alan L.
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