Process for isolation of anticancer agent camptothecin from...

Details Process for isolation of anticancer agent camptothecin from... Process for isolation of anticancer agent camptothecin from...

2005-05-17

2005-05-17

Tate, Christopher R. (Department: 1654)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Containing or obtained from a stem, stalk, branch, or twig,

C424S725000, C514S279000, C514S280000, C514S285000, C546S023000, C546S048000

Reexamination Certificate

active

06893668

ABSTRACT:
The present invention relates to an improved and economical process for the isolation of anticancer agent Camptothecin from the twigs and stem ofNothapodytes foetidausing hot extraction 20(S) Camptothecin is an alkaloid, which contains a pentacyclic ring system that includes a pyrrolo [3,4-b] quinoline moiety (ring A, B and C), the pyridone ring D and a chiral center at C-20 in ring E.

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Govindachari et al. Phytochemistry. 1972. vol. 11, No. 12, pp. 3529-3531.

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